CO129-468 - Governor Sir Stubbs - 1921 [6-8] — Page 101

be large. 4.This dess is probably frequently repeated,

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That the intra-uterine period may be dangerous to the child from the point of view

of tuberculosis has been definitely proved, though the cases en reserd ro rary -

coptional. Thus Schmorl and Birch-hirschfeld, and Sohworl and Keskel have described

cases in which the basilli were found in the placentas and the feet ses of tuber-

euleus mothers. More recently Friedmanın reparted the finding of two cases of tuber-

culeus infection by the plasental route.

So much for the question of hereditary tranmission of the bacillus tubersulesia.

As regards envirement ne eno new disputes the importance of this faster in pridus- ing the disease,but though womparison is difficult in human beings swing to the variety of disturbing factors, as has almondy been stated,in animals we can better arrange venditions to sit our purpose. The experiments of Truksnu may be referred te in this connection. He inoculated rabbits with tubersulesia and allowed sons to rum wild, whereas others were kept in a damp,dark place. Most of the former receverai,

while the latter rapidly museumbed.

In eattle an analogous condition is found; no MeFadyenn statest "All breeds and strains of cattle are susceptible to tubersulesis, and when the environment is the same the insidmos of the disease is the same in all breeds and strains." He found

that the conditions under which the cattle ware bred and reared constituted the

most important contributory faster according to the oppertunity supplied by the environment for the transmission of the basilli. Begardless of breed as a separate factor, the propertien of cases of tuberculosis furnished by any brood is high or low according so the cattle are or are net in slese association with other diseased animals. Onlmotto's experimenta lend additional support to the same fast. He found that sattle which had been ende infested nearly always recovered if they were sure- fully leslated, but if kept in prolengel sentast with tuberculeus animals they

themselves besamo netively tubersuleus.

Be in man ne race is exempt; in other words there is a racial musceptibility to tuberculeus infection,but there is not sufficient evidence at present to mable ens to say that any mesial predisposition is handed en by tuberculous parents to their

offspring.

To may summarise the matter by mying: firstly, that hereditary tranmission of the bacillus is so rare that for practical purposes it may be declared negligiblej sesondly, that the incidence ofź tuberculosis dependa en two main fusters, namely the dese received and the virulence of the strain inssulated; in other words the